Core Group of COVID literature collected by UCSF Internist Sachin Shah.

Literature review up to Marh 25, compiled by the ID Fellows at Emory

Epidemiology

Chen et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. The Lancet. 2020.

Ferguson et al. Impact of non-pharmaceutical interventions (NPIs) to reduce COVID-19 mortality and healthcare demand. Imperial College London. March 16, 2020.

Ki et al. Epidemiologic characteristics of early cases with 2019 novel coronavirus (2019-nCoV) disease in Korea. Epidemiol Health. 2020.

Lin, Xihong. Analysis of 25,000+ COVID-19 cases in Wuhan: Epidemiological characteristics and effects of non-pharmaceutical interventions. Webinar, slides. 2020.

Field Brief: Diamond Princess COVID-19 Cases. National Institute of Infectious Diseases.

Li et al. Substantial undocumented infection facilitates the rapid dissemination of novel coronavirus (SARS-CoV2). Science. March 16, 2020. - Based on Wuhan models, estimated 86% of true positive COVID cases are undocumented.

Clinical Course

Lei et al. Clinical characteristics and outcomes of patients undergoing surgeries during the incubation period of COVID-19 infection. E Clinical Medicine. April 4, 2020.

Arentz et al. Characteristics and Outcomes of 21 Critically Ill Patients with COVID-19 in Washington State. JAMA. March 19, 2020. - For severe ICU patients, 67% mortality and 10% discharge.

Weiss and Murdoch. Clinical course and mortality risk of severe COVID-19. The Lancet. March 17, 2020.

Guan et al. Clinical Characteristics of Coronavirus Disease 2019 in China. NEJM. 2020

Hu et al. Clinical characteristics of 24 asymptomatic infections with COVID-19 screened among close contacts in Nanjing, China. Science China Life Sciences. 2020.

Wang et al. Clinical Characteristics of 138 Hospitalized Patients with 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China. JAMA. 2020.

Wu et al. Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China: Summary of a Report of 72314 Cases From the Chinese CDC. JAMA. 2020.

Yanh et al. Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study. The Lancet Respiratory Medicine. 2020.

Zhou et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. The Lancet. 2020.

Holshue et al. First Case of 2019 Novel Coronavirus in the United States. NEJM. 2020.

Pan et al. Clinical characteristics of COVID-19 patients with digestive symptoms in Hubei, China: a descriptive, cross-sectional, multicenter study. Amer Jour Gastroenterology. 2020. - Study suggesting some COVID-19 patients present with GI Sx as primary complaint - and 7% as only complaint.

Testing

Peng et al. Findings of lung ultrasonography of novel coronavirus pneumonia during the 2019-2020 epidemic. Intensive Care Med. 2020.

Xie et al. Chest CT for Typical 2019-nCoV Pneumonia: Relationship to Negative RT-PCR Testing. Radiology. 2020.

Zhao et al. Relation Between Chest CT Finding and Clinical Conditions of Coronavirus Disease (COVID-19) Pneumonia: A Multicenter Study. American Journal of Roentgenology. 2020.

FDA greenlights first 45-minute, point-of-care coronavirus diagnostic test.

PPE/Masks

Santarpia et al. Transmission Potential of SARS-CoV-2 in Viral Shedding Observed at the University of Nebraska Medical Center. medRxiv. March 26, 2020. - Study showing that the virus can be found in up to 85% of objects in a patient’s room, even up to day 18 of hospitalization. 66% of samples of the HALLWAY outside the rooms were positive too.

Doremalen et al. Aerosol and Surface Stability of SARS-CoV-2 as Compared with SARS-CoV-1. NEJM 2020.

Kampf et al. Persistence of cornaviruses on inanimate surfaces and their inactivation with biocidal agents. Journal of Hospital Infection. 2020.

MacIntyre et al. A cluster randomised trial of cloth masks compared with medical masks in healthcare workers. BMJ Open. 2015.

Boston Children’s Hospital: Reusable Elastomeric Respirator.

Stanford Recommendations for Face Mask Shortages. March 22, 2020. - Evidence that N95s can be re-used after 70C in oven 30 min.

SAGES Recommendations for Re-using N95 Masks

Nebraska Medicine Protocol for Decontaminating N95 Masks with UV

Treatments

Wang et al. Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCov) in vitro. Cell Research. 2020.

Russell et al. Clinical evidence does not support corticosteroid treatment for 2019-nCoV lung injury. The Lancet. 2020.

Lim et al. The Application of Lopinavir/Ritonavir for the Treatment of COVID-19 Pneumonia Monitored by Quantitative RT-PCR. JKMS. 2020.

Shen et al. Treatment of 5 Critically Ill Patients With COVID-19 With Convalescent Plasma. JAMA. March 27, 2020. - First data showing plasma transfusion improved fevers and viral loads within 12 days of transfusion.